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   Immune Modeling of HIV

Disclaimer: The reprints available here are provided for your personal use only and may not be used for any commercial purpose without prior written permissions from the paper's publisher and author. The violation is subject to the U.S. Copyright Act of 1976, Title 17 U.S.C.

Qin, S, Junecko, B, Lucero, c, Klamar, C, Trichel, A, Murphey-Corb, M, Tarwater, P, Kirschner, D, Reinhart, T., Simian immunodeficiency Virus Infection Potently Modulates Chemokine Networks and Immune Environments in Hilar Lymph Nodes of Cynomolgus Macaques, JAIDS, 2013 Aug 1;63(4):428-37, DOI: 10.1097/QAI.0b013e31828ac85f, PMID: 23429503, PMCID: 3688692

Qin, S, Junecko, BAF, Trichel,, AM, Tarwater, PM, Murphy-Corb, MA, Kirschner, DE and Reinhart, T., Simian Immunodeficiency Virus Infection Alters Chemokine Networks in Lung Tissues of Cynomolgus Macaques : Association with Pneumocystis carinii Infection . The American Journal of Pathology, Vol. 177, No. 3, 2010, PMID: 20671263, PMCID: 2928961

Amy L. Bauer, Ian B. Hogue, Simeone Marino, and Denise E. Kirschner The Effects of HIV-1 Infection on Latent Tuberculosis . Math. Model. Nat. Phenom. Vol. 3, No. 7, 2008, pp. 229-266, PMID: n/a, PMCID: n/a

Shulin Qin, Yongjun Sui, Adam C. Soloff, Beth A. Fallert Junecko, Denise E. Kirs chner, Michael A. Murphey-Corb, Simon C. Watkins, Patrick M. Tarwater, James E. Pease, Simon M. Barratt-Boyes, and Todd A. Reinhart Chemokine and Cytokine Mediated Loss of Regulatory T Cells in Lymph Nodes during Pathogenic Simian Immunodeficiency Virus Infection . Journal of Immunology 180:5530-5536, 2008, PMID: 18390737, PMCID: 2567810

Fallert, BA, Poveda, S, Schaefer, T, Pfeifer, ME, Sanghavi, SK, Watkins, SC, Murphey-Corb, MA, Tarwater, PM, Kirschner, DE, Reinhart, TA, Virological and Immunologic Events in Hilar Lymph Nodes During Simian Immunodeficiency Virus Infection: Development of Polarized Inflammation. Journal of the Acquired Immune Deficiency Syndromes 47(1):16-26, 2008, PMID: 17971706, PMCID: n/a

Ian B. Hogue, Seema H. Bajaria, Beth A. Fallert, S hulin Qin, Todd A Reinhart, and Denise E. Kirschner The dual role of dendritic cells in the immune response to human immunodeficiency virus type 1 infection. Journal of General Virology, 2008, Volume 89: pp. 2228 - 2239, DOI: 10.1099/vir.0.83600-0, PMID: 18753232, PMCID: 2655655

Errata - Hogue et al

Supplement to the JGV article is available here (1).

A review of the JGV article called HIV by numbers from Microbiology Today is available here (2).

Todd M. Schaefer, Craig L. Fuller, Shrabani Basu, Beth A. Fallert, Sandra L. Poveda, Sonali K. Sanghavi, Yang-Kyu Choi, Denise E. Kirschner, Eleanor Feingold, Todd A. Reinhart Increased expression of interferon-inducible genes in macaque lung tissues during simian immunodeficiency virus infection. Microbes and Infection - Published by Elsevier SAS, 2006., PMID: 16822691, PMCID: (exempt)

Seema H. Bajaria, Denise E. Kirschner. CTL action during HIV-1 is determined via interactions with multiple cell types. Deterministic and Stochastic Models for AIDS Epidemics and HIV Infection with Interventions, Eds: W.Y. Tan and Hulin Wu . Published by World Scientific, Singapore and River Edge, New Jersey, pp. 219-254, 2005, PMID: n/a, PMCID: (exempt)

Ping Ye, Athena P. Kourtis, Denise E. Kirschner. The Thymus During HIV Disease: Role in Pathogenesis and in Immune Recovery. Current HIV Research, vol 2:177-183, 2004, PMID: 15078181, PMCID: (exempt)

Seema H. Bajaria, Glenn Webb, Denise E. Kirschner. Predicting Differential Responses to Structured Treatment Interruptions During HAART. Bulletin of Mathematical Biology, 66:1093-1118, 2004, PMID: 15294419, PMCID: (exempt)

Ping Ye, Powel Kazanjian, Steven L. Kunkel, and Denise E. Kirschner Lack of good correlation of serum CC-chemokine levels with human immunodeficiency virus-1 disease stage and response to treatment J Lab and Clin Medicine, 143:310-319, 2004, PMID: 15122175, PMCID: (exempt)

Ping Ye, Athena Kourtis, Denise Kirschner. Reconstitution of thymic function in HIV-1 patients treated with highly active anti-retroviral therapy. Clin Immunology, 106:95-105, 2003, PMID: 12672400, PMCID: (exempt)

Ping Ye and Denise E. Kirschner Measuring Emigration of Human Thymocytes by T-Cell Receptor Excision Circles. Crit Rev Immuno 22:483-498, 2002, PMID: 12803323, PMCID: (exempt)

Ping Ye, Athena Kourtis, Denise Kirschner. The effects of different HIV type I strains on human thymic function. AIDS Res Human Retroviruses, 18:1239-1251, 2002, PMID: 12487812, PMCID: (exempt)

Ping Ye and Denise Kirschner, Reevaluation of T cell receptor excision circles as a measure of human recent thymic emigrants. J Immunology 169:4968-4979, 2002, PMID: 11994448, PMCID: (exempt)

Seema H. Bajaria, Glenn Webb, Miles Cloyd, Denise E. Kirscher, Dynamics of Naive and Memory CD4+ T Lymphocytes in HIV-1 Disease Progression J AIDS & Hum Retrov 30:41-58, 2002, PMID: 12048362, PMCID: (exempt)

Liancheng Wang, Michael Y. Li, Denise Kirschner, Mathematical analysis of the global dynamics of a model for HTLV-I infection and ATL progression Math Biosciences 179:207-217, 2002, PMID: n/a, PMCID: (exempt)

Errata - (1).

Jorge X. Velasco-Hernandez, Jose A. Garcia,Denise E. Kirschner , Remarks on Modeling Host-Viral Dynamics and Treatment. in: Volume 125: Mathematical Approaches for Emerging and Reemerging Infectious Diseases Part I: An Introduction to Models, Methods, and Theory
In: Chavez C, Blower S, Van Den Dreische P, Kirschner D, Yakubu A-A. (eds): Mathematical Approaches for Emerging and Reemerging Infectious Diseases: An Introduction to Models, Methods and Theory. Vols. 1 and 2, (Springer-Verlag, New York, 2001), PMID: n/a, PMCID: (exempt)

Kirschner D, Webb GF and Cloyd M. A model of HIV-1 disease progression based on virus-induced lymph node homing and homing-induced apoptosis of CD4+ T lymphocytes. J. AIDS, 24:352-362, 2000, PMID: 11015152, PMCID: (exempt)

Covert D and Kirschner D. Revisiting Early Models of the host-pathogen interactions in HIV infection, Comments on Theoretical Biology, 5:383-411, 2000, PMID: n/a, PMCID: (exempt)

Sanchez-Garduno F, Kirschner D and Reynolds J. Key dynamics from a simple model of HIV infection. In: Mathematical Models in Medical and Health Sciences, Horn MA, Simonett G, Webb GF (eds), Vanderbilt University Press, Nashville, pp. 161-196, 1999, PMID: n/a, PMCID: (exempt)

Kirschner D. Dynamics of co-infection with M. tuberculosis and HIV-1. Theor Popul Biol, 55: 94-109, 1999., PMID: 9925811, PMCID: (exempt)

Kirschner D and Webb GF. Immunotherapy of HIV-1 infection. J Biol Systems, 6:71-83, 1998, PMID: n/a PMCID: (exempt)

Kirschner D, Mehr R and Perelson A. The role of the thymus in pediatric HIV-1 infection. J AIDS & Human Retrov, 18:95-109, 1998, PMID: 9637574, PMCID: (exempt)

Kirschner D and Morgan J. Solution of the asymmetric mixing problem. SIAM J Appl Math, 58: 725-736, 1998, PMID: n/a, PMCID: (exempt)

Kirschner D and Webb GF. A mathematical model of combined drug therapy of HIV infection. J Theor Med 1:25-34, 1998, PMID: n/a, PMCID: (exempt)

Butler S, Kirschner D and Lenhart S. Optimal control of Chemotherapy Affecting the Infectivity of HIV . In: Arino O, Axelrod D, Kimmel M, (eds): Advances in Mathematical Population Dynamics-Molecules, Cells and Man, Series in Mathematical Biology and Medicine, Vol. 6 (World Scientific, Singapore, 1997) pp. 104-120, PMID: n/a, PMCID: (exempt)

Kirschner D, Lenhart S, Serbin S. Optimal control of the chemotherapy of HIV J Math Biol 35:775-792, 1997, PMID: 9269736, PMCID: (exempt)

Kirschner D and Webb GF. Qualitative differences in HIV chemotherapy between resistance and remission outcomes. Emerging Inf Dis 3:273-283, 1997, PMID: 9284371, PMCID: 2627652

Kirschner D and Webb GF. Understanding drug resistance for montherapy treatment of HIV infection . Bull Math Biol 59:763-786, 1997, PMID: 9214852, PMCID: (exempt)

Kirschner D. Using mathematics to understand HIV immune dynamics. AMS Notices pp. 191-202, February 1996, PMID: n/a, PMCID: (exempt)

Errata - (1).

Kirschner D and Webb GF. A model for treatment strategy in the chemotherapy of AIDS. Bull Math Biol 58:367-390, 1996, PMID: 8713663, PMCID: (exempt)

Kirschner D and Perelson A. A Model for the Immune System Response to HIV: AZT Treatment Studies . In: Arino O, Axelrod D, Kimmel M, Langlais M (eds): Mathematical Population Dynamics: Analysis of Hetergeneity and Theory of Epidemics (Wuerz Publishing, Winnipeg, 1995) pp. 295-310, PMID: n/a, PMCID: (exempt)

Perelson A, Kirschner D, De Boer R. The dynamics of HIV infection of CD4+ T cells. Math Biosci 114:81-125, 1993, PMID: 8096155, PMCID: (exempt)

In honor of Professor Glen F. Webb's 65th birthday, we would like to refer you to a special issue of Mathematical Modelling of Natural Phenomena   dedicated to Glen.


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