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Immune Modeling of HIV
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Qin, S, Junecko, B, Lucero, c, Klamar, C, Trichel, A, Murphey-Corb,
M, Tarwater, P, Kirschner, D, Reinhart, T.,
Simian immunodeficiency Virus Infection Potently Modulates Chemokine Networks and Immune
Environments in Hilar Lymph Nodes of Cynomolgus Macaques,
JAIDS, 2013 Aug 1;63(4):428-37,
DOI: 10.1097/QAI.0b013e31828ac85f,
PMID: 23429503,
PMCID: 3688692
Qin, S, Junecko, BAF, Trichel,, AM, Tarwater, PM, Murphy-Corb, MA, Kirschner, DE
and Reinhart, T.,
Simian Immunodeficiency Virus Infection Alters
Chemokine Networks in Lung Tissues of Cynomolgus Macaques : Association with
Pneumocystis carinii Infection
.
The American Journal of Pathology, Vol. 177, No. 3, 2010,
PMID: 20671263,
PMCID: 2928961
Amy L. Bauer, Ian B. Hogue, Simeone Marino, and Denise E. Kirschner
The Effects of HIV-1 Infection on Latent Tuberculosis
.
Math. Model. Nat. Phenom.
Vol. 3, No. 7, 2008, pp. 229-266,
PMID: n/a,
PMCID: n/a
Shulin Qin, Yongjun Sui, Adam C. Soloff, Beth A. Fallert Junecko, Denise E. Kirs
chner, Michael A. Murphey-Corb, Simon C. Watkins, Patrick M. Tarwater, James E.
Pease, Simon M. Barratt-Boyes, and Todd A. Reinhart
Chemokine and Cytokine Mediated Loss of Regulatory
T Cells in Lymph Nodes during
Pathogenic Simian Immunodeficiency Virus Infection
.
Journal of
Immunology 180:5530-5536, 2008,
PMID: 18390737,
PMCID: 2567810
Fallert, BA, Poveda, S, Schaefer, T, Pfeifer, ME, Sanghavi, SK,
Watkins, SC, Murphey-Corb, MA, Tarwater, PM, Kirschner, DE, Reinhart, TA,
Virological and Immunologic Events in Hilar Lymph Nodes During Simian
Immunodeficiency Virus Infection: Development of Polarized Inflammation.
Journal of the Acquired Immune Deficiency Syndromes 47(1):16-26, 2008,
PMID: 17971706,
PMCID: n/a
Ian B. Hogue, Seema H. Bajaria, Beth A. Fallert, S
hulin Qin, Todd A Reinhart, and Denise E. Kirschner
The dual role of dendritic cells in the immune response
to human immunodeficiency virus type 1 infection.
Journal of General Virology, 2008,
Volume 89: pp. 2228 - 2239,
DOI: 10.1099/vir.0.83600-0,
PMID: 18753232,
PMCID: 2655655
Errata -
Hogue et al
Supplement to the JGV article is available here
(1).
A review of the JGV article called HIV by numbers
from Microbiology Today
is available here
(2).
Todd M. Schaefer, Craig L. Fuller, Shrabani Basu, Beth A. Fallert,
Sandra L. Poveda, Sonali K. Sanghavi, Yang-Kyu Choi,
Denise E. Kirschner, Eleanor Feingold, Todd A. Reinhart
Increased expression of interferon-inducible genes in macaque
lung tissues during simian immunodeficiency virus infection.
Microbes and Infection - Published by Elsevier SAS, 2006.,
PMID: 16822691,
PMCID: (exempt)
Seema H. Bajaria, Denise E. Kirschner.
CTL action during HIV-1 is determined via
interactions with multiple cell types.
Deterministic and Stochastic Models for AIDS Epidemics and HIV Infection
with Interventions, Eds: W.Y. Tan and Hulin Wu . Published by World
Scientific, Singapore and River Edge, New Jersey, pp. 219-254, 2005,
PMID: n/a,
PMCID: (exempt)
Ping Ye, Athena P. Kourtis, Denise E. Kirschner.
The Thymus During HIV Disease: Role in Pathogenesis and in Immune
Recovery.
Current HIV Research, vol 2:177-183, 2004,
PMID: 15078181,
PMCID: (exempt)
Seema H. Bajaria, Glenn Webb, Denise E. Kirschner.
Predicting Differential Responses to Structured Treatment
Interruptions During HAART.
Bulletin of Mathematical Biology, 66:1093-1118, 2004,
PMID: 15294419,
PMCID: (exempt)
Ping Ye, Powel Kazanjian, Steven L. Kunkel, and Denise E. Kirschner
Lack of good correlation of serum CC-chemokine levels with human
immunodeficiency virus-1 disease stage and response to treatment
J Lab and Clin Medicine, 143:310-319, 2004,
PMID: 15122175,
PMCID: (exempt)
Ping Ye, Athena Kourtis, Denise Kirschner.
Reconstitution of thymic function in HIV-1 patients treated with highly
active anti-retroviral therapy.
Clin Immunology, 106:95-105, 2003,
PMID: 12672400,
PMCID: (exempt)
Ping Ye and Denise E. Kirschner
Measuring Emigration of Human Thymocytes by
T-Cell Receptor Excision Circles.
Crit Rev Immuno 22:483-498, 2002,
PMID: 12803323,
PMCID: (exempt)
Ping Ye, Athena Kourtis, Denise Kirschner.
The effects of different HIV type I strains on human thymic function.
AIDS Res Human Retroviruses, 18:1239-1251, 2002,
PMID: 12487812,
PMCID: (exempt)
Ping Ye and Denise Kirschner,
Reevaluation of T cell receptor excision circles as a measure of human recent thymic emigrants.
J Immunology 169:4968-4979, 2002,
PMID: 11994448,
PMCID: (exempt)
Seema H. Bajaria, Glenn Webb, Miles Cloyd, Denise E. Kirscher,
Dynamics of Naive and Memory CD4+ T Lymphocytes in
HIV-1 Disease Progression
J AIDS & Hum Retrov 30:41-58, 2002,
PMID: 12048362,
PMCID: (exempt)
Liancheng Wang, Michael Y. Li, Denise Kirschner,
Mathematical analysis of the global dynamics of a model for HTLV-I
infection and ATL progression
Math Biosciences 179:207-217, 2002, PMID: n/a, PMCID: (exempt)
Errata -
(1).
Jorge X. Velasco-Hernandez, Jose A. Garcia,Denise E. Kirschner ,
Remarks on Modeling Host-Viral Dynamics and
Treatment.
in: Volume 125: Mathematical Approaches for Emerging and
Reemerging Infectious Diseases Part I: An Introduction to Models, Methods, and Theory
In: Chavez C, Blower S, Van Den Dreische P, Kirschner D, Yakubu A-A. (eds): Mathematical Approaches for Emerging and Reemerging Infectious Diseases:
An Introduction to Models, Methods and Theory. Vols. 1 and 2,
(Springer-Verlag, New York, 2001), PMID: n/a, PMCID: (exempt)
Kirschner D, Webb GF and Cloyd M.
A model of HIV-1 disease progression based on virus-induced lymph node homing and
homing-induced apoptosis of CD4+ T lymphocytes.
J. AIDS, 24:352-362, 2000,
PMID: 11015152,
PMCID: (exempt)
Covert D and Kirschner D.
Revisiting Early Models of the
host-pathogen interactions in HIV infection,
Comments on Theoretical Biology, 5:383-411, 2000,
PMID: n/a, PMCID: (exempt)
Sanchez-Garduno F, Kirschner D and Reynolds J.
Key dynamics from a simple model of HIV infection.
In: Mathematical Models in Medical and Health Sciences, Horn MA,
Simonett G, Webb GF (eds), Vanderbilt University Press, Nashville, pp.
161-196, 1999, PMID: n/a,
PMCID: (exempt)
Kirschner D. Dynamics of co-infection with M. tuberculosis and
HIV-1.
Theor Popul Biol, 55: 94-109, 1999.,
PMID: 9925811,
PMCID: (exempt)
Kirschner D and Webb GF.
Immunotherapy of HIV-1 infection.
J Biol Systems, 6:71-83, 1998,
PMID: n/a
PMCID: (exempt)
Kirschner D, Mehr R and Perelson A.
The role of the thymus in pediatric HIV-1 infection.
J AIDS & Human Retrov, 18:95-109, 1998,
PMID: 9637574,
PMCID: (exempt)
Kirschner D and Morgan J.
Solution of the asymmetric mixing
problem. SIAM J Appl Math, 58: 725-736, 1998,
PMID: n/a, PMCID: (exempt)
Kirschner D and Webb GF.
A mathematical model of combined drug
therapy of HIV infection. J Theor Med 1:25-34, 1998,
PMID: n/a, PMCID: (exempt)
Butler S, Kirschner D and Lenhart S.
Optimal control of
Chemotherapy Affecting the Infectivity of HIV
.
In: Arino O, Axelrod D, Kimmel M, (eds): Advances in Mathematical
Population Dynamics-Molecules, Cells and Man, Series in Mathematical Biology and Medicine,
Vol. 6 (World Scientific, Singapore, 1997) pp. 104-120,
PMID: n/a,
PMCID: (exempt)
Kirschner D, Lenhart S, Serbin S. Optimal control of the chemotherapy of HIV
J Math Biol 35:775-792, 1997,
PMID: 9269736,
PMCID: (exempt)
Kirschner D and Webb GF.
Qualitative differences in HIV
chemotherapy between resistance and remission outcomes.
Emerging Inf Dis 3:273-283, 1997,
PMID: 9284371,
PMCID: 2627652
Kirschner D and Webb GF.
Understanding drug resistance for
montherapy treatment of HIV infection
. Bull Math Biol 59:763-786, 1997,
PMID: 9214852,
PMCID: (exempt)
Kirschner D.
Using mathematics to understand HIV immune dynamics.
AMS Notices pp. 191-202, February 1996,
PMID: n/a,
PMCID: (exempt)
Errata -
(1).
Kirschner D and Webb GF.
A model for treatment strategy in the
chemotherapy of AIDS. Bull Math
Biol 58:367-390, 1996,
PMID: 8713663,
PMCID: (exempt)
Kirschner D and Perelson A.
A Model for the Immune System
Response to HIV: AZT Treatment Studies
. In: Arino O, Axelrod D, Kimmel
M, Langlais M (eds): Mathematical Population Dynamics: Analysis of
Hetergeneity and Theory of Epidemics (Wuerz Publishing,
Winnipeg, 1995) pp. 295-310,
PMID: n/a,
PMCID: (exempt)
Perelson A, Kirschner D, De Boer R.
The dynamics of HIV infection
of CD4+ T cells. Math Biosci 114:81-125, 1993,
PMID: 8096155,
PMCID: (exempt)
In honor of Professor Glen F. Webb's 65th birthday,
we would like to refer you to a special issue of
Mathematical Modelling of Natural Phenomena
dedicated to Glen.
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