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An online supplement for Neutrophil dynamics affect Mycobacterium tuberculosis granuloma outcomes and dissemination

[ Video Homepage | Kirschner Lab Time-Lapse Simulations Homepage ]

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Video 7B: Granuloma undergoing dissemination (days 6-8 PI)

To play the video, click on the graphic image above Infected neutrophil facilitates dissemination. An infected neutrophil dies and leaves extracellular Mtb on the grid between days 7 to 8 PI. Shown are the 2D xy- locations of the simulated agents over time, from days 6 to 8 PI. Macrophages (green -- resting, orange -- infected, red -- chronically infected, blue -- activated), T cells (cantaloupe -- Tgam, maroon -- Tcyt, cyan -- Treg), extracellular Mtb (brown cross). Cells infected with Mtb are outlined in black. Caseum not shown.

Time-lapse videos corresponding to Figure 3 snapshots in main paper. These are 6 different simulations of granulomas including neutrophils and showing different outcomes. Click on the video link for more details for each. GranSim produces simulated granulomas that reflect granulomas in experimentally-infected macaques.
Video 3A	Video 3B
Video 3C	Video 3D
Video 3E	Video 3F
Dissemination time-lapse videos corresponding to Figure 7A snapshot in main paper. These are 3 different simulations of dissemination granulomas including neutrophils and showing different outcomes. Click on the video link for more details for each. GranSim also produces simulated granulomas that reflect dissemination granulomas in experimentally-infected macaques.
Video 7A	Video 7B
Video 7C

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[ Video Homepage | Kirschner Lab Time-Lapse Simulations Homepage ]