Legend: Time-lapse of a simulated granuloma during the first 200 days post-infection (sample drawn from the full parameter set, see Table 1 and Appendix Table 1). This video corresponds to the granuloma shown in Figure 3, panel B. Here, we use a color scheme that distinguishes among the different simulated cell types: Macrophages (green-- resting, orange-- infected, red-- chronically infected, blue-- activated), Neutrophils (purple), T cells (Tgam-- pink, Tcyt-- maroon, Treg-- cyan), extracellular Mtb (brown), and caseum (beige) are shown.
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