Multiscale 3D Granuloma Simulations

Multiscale 3D Granuloma Simulations
[ Multiscale 3D Granuloma Simulations Homepage | Kirschner Lab Time-Lapse Simulations Homepage ]

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Movie 3: Visualizing the agents in 3D

The 3D xyz-locations of the simulated agents over time, from day 29 to 50. Macrophages (orange -- infected, red -- chronically infected, blue -- activated), T cells (yellow-orange -- Tgam, maroon -- Tcyt, cyan -- Treg), extracellular Mtb (not shown). In order to better visualize the interior of the granuloma, displayed agents are restricted to the subregion [0,99]x[0,51]x[0,99] of the xyz-grid and resting macrophages are not shown. A 2D mesh xy-slice displays the current TNF gradient at z=50, and it is not restricted to the subregion of the agents. Grid compartments in which there have been at least one cell death contributing to caseum formation are enclosed by a light gray, semi-transparent 3D surface. The display of this caseum 'surface' is not restricted to the above sub-region, and instead reflects the entire 100x100x100 grid.

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Movie 1	Movie 2
Visualizing z-slices of the three different simulated chemical gradients over time	Visualizing the simulated Tumor necrosis factor (TNF) chemical gradient at day 50 through slices and surfaces
Movie 3	Movie 4
Visualizing the agents in 3D	Visualizing the agents through a single z-slice of the 3D simulated data

[ Multiscale 3D Granuloma Simulations Homepage | Kirschner Lab Time-Lapse Simulations Homepage ]