Multiscale 3D Granuloma Simulations

Multiscale 3D Granuloma Simulations
[ Multiscale 3D Granuloma Simulations Homepage | Kirschner Lab Time-Lapse Simulations Homepage ]

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Movie 1: Visualizing z-slices of the three different simulated chemical gradients over time

Example of molecular diffusion of different molecules in the GranSim environment. The top three layers show three different molecules (top layer -- IL-10, middle layer -- TNF, lower layer -- CCL5) diffusing in a 3D environment of 2mmx2mmx2mm, with100x100x100 microcompartments. The relative concentrations of the molecules in each microcompartment are shown as a heatmap gradient. The three layers correspond to 2D mesh xy-slices of the same random seed, for z-values of 94, 59, and 24, respectively. The xyz-locations of vascular sources (light blue cubes) are also shown, restricted here to those with a z-value of 0. Vascular sources denote sites at which new cells can enter the grid. Shown axes are xyz-positive. The movie is over time, and corresponds to days 28 to 50 in the simulation.

To play the movie, click on the graphic image above

Right click or CTRL-click on MP4 icon,
select "Save Link As" or "Save Target As"
to download the archived MP4 movie file version of
Movie 1.

To extract the MP4 movie from the archive, download the archive
to your Mac or Windows desktop, double-click on them, and follow the
on-screen instructions.

To extract on Linux, Unix, BSD, etc... use the command in a shell
'unzip (filename.zip)' or a desktop extraction utility.

Movie 1	Movie 2
Visualizing z-slices of the three different simulated chemical gradients over time	Visualizing the simulated Tumor necrosis factor (TNF) chemical gradient at day 50 through slices and surfaces
Movie 3	Movie 4
Visualizing the agents in 3D	Visualizing the agents through a single z-slice of the 3D simulated data

[ Multiscale 3D Granuloma Simulations Homepage | Kirschner Lab Time-Lapse Simulations Homepage ]