Inhaled Antibiotic Treatment Simulations
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an on-line supplement for A systems pharmacology approach towards the design of inhaled formulations of rifampicin and isoniazid for treatment of tuberculosis |
[ Kirschner Lab Time-Lapse Simulations Homepage ]
Cilfone, N, Pienaar, E, Thurber, G, Kirschner, D and Linderman, JJ.,
A systems pharmacology approach towards the design of inhaled formulations
of rifampicin and isoniazid for treatment of tuberculosis,
CPT Pharmacometrics Syst. Pharmacol. (2015) 4, e22,
DOI: 10.1002/psp4.22,
PMID: 26225241,
PMCID: 4394619
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| Supplementary 1: | Methods |
| Supplementary 2: | Figures |
| Supplementary 3: | Model Parameters |
 Movie 1 |
 Movie 2 |
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Time lapse of a single inhaled dose over a 14 day treatment window.
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Time lapse of INH dynamics over a 14 day treatment window.
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 Movie 3 |
 Movie 4 |
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Time lapse of granuloma dynamics over a 14 day treatment window. |
Time lapse of RIF dynamics over a 14 day treatment window. |
 Movie 5 |
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Time lapse of granuloma dynamics over a 14 day treatment window. |
| [ Kirschner Lab Time-Lapse Simulations Homepage ] |