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Time Lapse Simulations of Agent Based Models
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Supplement 1: Agent-Based Model Rules 143k Supplement 2: Detailed Methods 83k Supplement 3: Supplementary Tables and Figures 37M

Time-Lapse Simulation of controlled infection Time-lapse simulation of a granuloma forming after infection with Mycobacterium tuberculosis. The field simulates a 2 mm by 2 mm slice of lung parenchyma where an infected macrophage cell initates the infection. Recruited immune cells arrive via vascular sources distributed on the parenchyma. The movie shows 200 days of infection dynamics. This simulation represents a controlled infection where a stable granuloma forms. Right click or CTRL-click on MPEG icon, select "Save Link As" or "Save Target As" to download the archived MPEG movie file version of time-lapse simulations of controlled infection To extract the MPEG movie from the archive, download the archive to your Mac or Windows desktop, double-click on them, and follow the on-screen instructions. To extract on Linux, Unix, BSD, etc... use the command in a shell 'unzip (filename.zip)' or a desktop extraction utility Flash time-lapse simulations are best played using Flash version 8 or greater

Time-Lapse Simulations of TNF Deletion Time-lapse simulation of a granuloma forming after infection with Mycobacterium tuberculosis in the absence of tumor necrosis factor-α (TNF). This simulation has identical conditions to the control simulation (above), except that TNF is not produced by host immune cells. Right click or CTRL-click on MPEG icon, select "Save Link As" or "Save Target As" to download the archived MPEG movie file version of time-lapse simulations of TNF Deletion To extract the MPEG movie from the archive, download the archive to your Mac or Windows desktop, double-click on them, and follow the on-screen instructions. To extract on Linux, Unix, BSD, etc... use the command in a shell 'unzip (filename.zip)' or a desktop extraction utility Flash time-lapse simulations are best played using Flash version 8 or greater

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All content and files © 2008, 2009 - Dr. Denise Kirschner - University of Michigan