Time Lapse Simulations of Agent Based Models
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Supplement 1: Agent-Based Model Rules 143k

Supplement 2: Detailed Methods 83k

Supplement 3: Supplementary Tables and Figures 37M






Time-Lapse Simulation of controlled infection

Time-lapse simulation of a granuloma forming after infection with Mycobacterium tuberculosis. The field simulates a 2 mm by 2 mm slice of lung parenchyma where an infected macrophage cell initates the infection. Recruited immune cells arrive via vascular sources distributed on the parenchyma. The movie shows 200 days of infection dynamics. This simulation represents a controlled infection where a stable granuloma forms.

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Flash time-lapse simulations are best played using Flash version 8 or greater





Time-Lapse Simulations of TNF Deletion

Time-lapse simulation of a granuloma forming after infection with Mycobacterium tuberculosis in the absence of tumor necrosis factor-α (TNF). This simulation has identical conditions to the control simulation (above), except that TNF is not produced by host immune cells.

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Flash time-lapse simulations are best played using Flash version 8 or greater


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