Multi-scale Modeling Consortium grant sponsored by NLM and NHLBI of the NIH

A multi-scale approach for understanding antigen presentation in immunity

SBML format of Models:

To make our models "sharing-friendly", we have prepared SBML format for the models in the papers in the following links that are derived from this study:

Fallahi-Sichani M, Flynn JL, Linderman JJ, Kirschner DE, Differential risk of tuberculosis reactivation among anti-TNF therapies is due to drug binding kinetics and permeability and not apoptotic and cytolytic activities, J. Immunology, 2012, The Journal of Immunology, April 1, vol. 188, no. 7, pp. 3169-3178, DOI: doi:10.4049/jimmunol.1103298, PMID: 22379032, PMCID: 352958

Guzzetta, G, Ajelli, M, Yang, Z, Merler, S, Furlanello, C, Kirschner, D. Modeling socio-demography to capture TB transmission in a low burden setting, J. Theor. Biology, Nov 21 2011. 289:197-205., PMID: 21906603, PMCID: 3208139

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